Cholesterol reducing agents inhibit assembly of type I parainfluenza viruses
نویسندگان
چکیده
منابع مشابه
Biology of parainfluenza viruses.
Parainfluenza virus types 1 to 4 (PIV1 to PIV4) are important human pathogens that cause upper and lower respiratory tract infections, especially in infants and children. PIV1, PIV2, and PIV3 are second only to respiratory syncytial virus as a cause of croup in young children. Although some clinical symptoms are typical of PIVs, etiologic diagnosis always requires detection of infectious virus,...
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Serologic cross reactions have been demonstrated between members of the parainfluenza subgroup of myxoviruses.7'-Similar antigenic relationships have also been noted between mumps virus and each of the four parainfluenza virus serotyes" and between mumps and Newcastle disease virus.7'8 Furthermore, the DA virus, § a myxovirus recently isolated from human blood, which is serologically indistingu...
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Myopericarditis is not uncommon, but often under-diagnosed. In fulminant cases, it may lead rapidly to circulatory failure or malignant arrhythmia, causing mortality. In this report, we describe a 41-year-old man who had episodes of convulsion one week after an upper respiratory tract infection. His electrocardiograms (ECGs) recorded during attack showed ventricular tachycardia. He had pulmonar...
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Three lectins with different sugar binding specificities were investigated for anti-viral activity against human parainfluenza virus type 2 (hPIV-2). The lectins, concanavalin A (Con A), lens culinaris agglutinin (LCA) and peanut agglutinin (PNA), inhibited cell fusion and hemadsorption induced by hPIV-2. Virus nucleoprotein (NP) gene synthesis was largely inhibited, but fusion (F) and hemagglu...
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The survival of human parainfluenza virus types 1, 2, and 3 was measured in both indoor and outdoor environments at South Pole Station, Antarctica, in an effort to determine the long-term survival of these viruses in this environment and to identify the possible source of respiratory tract illnesses which occurred in this isolated population in 1978 after 10 and 27 weeks of total social isolati...
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ژورنال
عنوان ژورنال: Virology
سال: 2017
ISSN: 0042-6822
DOI: 10.1016/j.virol.2016.11.011